Gynecologic oncology is a specialized field of medicine that focuses on cancers of the female reproductive system, including ovarian cancer, uterine cancer, vaginal cancer, cervical cancer, and vulvar cancer. As specialists, they have extensive training in the diagnosis and treatment of these cancers.
- PE is used for recurrent cervical carcinoma, both squamous and adenocarcinoma, with well-documented salvage potential.
- Up to 25% of women with FIGO stage IB-IIA cervical cancer may recur after initialtherapy.
- Radical surgery offers an alternative curative treatment.
- Survival rates ranging from 16 to 60% are reported for these patients
- Long-term survival is directly correlated with complete tumor resection
- Pelvic Exenteration has also been utilized as a potentially curative primary treatmentfor locally advanced cervical cancer
- Cases of PE for a variety of histologic types of uterine cancer have been reported, with outcomes similar to PE for other indications.
- Women with loco-regional recurrence may be candidates for PE with curative intent.
- Morris et al.reported a five-year survival rate of 45% following PE for recurrent endometrial cancer.
- Vulvar cancer has a propensity for regional metastases.
- For patients with advanced primary or recurrent vulvar cancer who do not have the option of treatment with radiation therapy, PE may be appropriate
- This technique may be used to achieve optimal cytoreduction in patients with disease requiring bladder and rectosigmoid resection.
- Indications include intractable hemorrhage due to tumor invasion and fistulae.